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A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation.

Arthritis Res Ther · 2012 · PMC3392797 · PMID 22251404

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There was a trend for reduction in both IgG1 and IgG2a isotypes as well as total IgG anti-CII in TFM-C-treated mice compared to vehicle-treated mice (Figure 2D ), but the difference did not reach statistical significance.

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