RT-PCR analysis of other collagens, in particular Col3a1 and Col5a1 , significantly up-regulated in the Frzb -/- mice compared to wild-type mice in the microarray analysis, depicted a decreasing trend at Day 7 in FRZB overexpressing micro-masses compared to the control micro-masses; however, these comparisons did not reach statistical significance (Figure 4A ).
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Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice.
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