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Dysferlin and animal models for dysferlinopathy.

J Toxicol Pathol · 2012 · PMC3392904 · PMID 22907980

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Read-through by small-molecule drugs Phase IIb trials of ataluren (PTC124), which causes read-through for the nonsense mutation DMD/BMD, has been suspended or terminated because the primary endpoint did not reach statistical significance within the 48-week duration of the study (http://clinicaltrials.gov/ct2/results?term=PTC124).

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