a near-significant trendP < 0.07
Moreover, interim analysis indicated a near-significant trend ( P < 0.07) toward increased lifespan in the ALS group receiving dexpramipexole [ 21 ].
Moreover, interim analysis indicated a near-significant trend ( P < 0.07) toward increased lifespan in the ALS group receiving dexpramipexole [ 21 ].
It may be significant that most of the Mendelian factors associated with FALS code for proteins involved in cellular mass transport (either axonal transport or vesicle trafficking), or else code for proteins whose malfunction results in macromolecular aggregates that could impede these transport processes.