Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice.

Diabetes · 2012 · PMC3402321 · PMID 22698914

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did not reach statistical significanceno p-value reported

There was trend for a further reduction in nitrotyrosine staining with quinapril ( P = 0.08) and alagebrium in diabetic apoE RAGE double-KO mice, but these changes did not reach statistical significance ( Fig. 5 ).

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