Barely Significant
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Conformational analysis of Clostridium difficile toxin B and its implications for substrate recognition.

PLoS One · 2012 · PMC3402401 · PMID 22844485

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quite significantno p-value reported
In our simulation both mobile loops near the active site reach rmsf values of near 2 Å and thus undergo quite significant motions over time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.