Antigen-specific CD3ε + CD4 + T cells capable only of IL-10 production also showed a trend towards a reduction in frequency, but this was not significant (0.57±0.23% to 0.10±0.03%; p = ns; Figure 7B ).
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IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis.
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