Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle.

Skeletal muscle oxidative capacity Cytochrome c content measured by Western blotting showed no statistically significant differences between the groups (Figure 6A and 6B ), although high-fat diet had nearly significant (P = 0.072) main effect and combination of HF and exercise showed significance compared to LF sedentary group.

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