Mapping genetic variants associated with beta-adrenergic responses in inbred mice.

Hits were declared nominally significant for p -values ≤10 −8 and suggestive for p -values ranging from 10 −6 to 10 −8 ( Material and Methods , Figure S11 ).

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Highly significant hits mapped onto two ca 8 Mb-apart regions of chr 5, called loci 1 and 2 ( Table 1 , Figure 2 ).

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