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Total-tau in cerebrospinal fluid of patients with multiple sclerosis decreases in secondary progressive stage of disease and reflects degree of brain atrophy.

Ups J Med Sci · 2012 · PMC3410288 · PMID 22554142

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There was a trend to show higher T1-weighted and FLAIR lesion load in the SP group compared to RR patients, but this difference did not reach statistical significance.

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