Barely Significant
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Systemic therapy for advanced soft tissue sarcomas: highlighting novel therapies and treatment approaches.

Cancer · 2012 · PMC3412982 · PMID 21837668

Europe PMCDOI
1
hedged sentence
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

a slight trendP = .10so close (0.05 < p ≤ 0.1)
did not reach statistical significanceno p-value reported
A pooled analysis of 8 randomized clinical trials involving 2281 patients with STS demonstrated a slight trend favoring doxorubicin-based combination therapy for ORR (odds ratio [OR], 0.79; 95% confidence interval [95% CI], 0.60-1.05 [ P = .10]); these results, as well as OS data (OR, 0.84; 95% CI, 0.67-1.06 [ P = .13]), did not reach statistical significance compared with single-agent doxorubicin. 16 Nausea, vomiting, and myelosuppression were consistently more severe with the combination regimens.

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