Statin use is associated with a reduced incidence of colorectal cancer: a colonoscopy-controlled case-control study.

Cancer patients were significantly less likely to have used simvastatin than controls [OR = 0.43 (0.10 – 0.73), p<0.01] but although there was a similar numerical effect for other statins, given the smaller numbers, this did not reach statistical significance [OR = 0.49 (0.13 – 1.13), p = 0.09].

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Two separate studies showed a highly significant 50% reduction in CRC incidence in statin users [ 8 , 11 ].

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