Barely Significant
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The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway.

PLoS Negl Trop Dis · 2012 · PMC3424247 · PMID 22928053

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quite significantno p-value reported
Since the effects of ligand binding on energy calculations in PISA may be quite significant [37] and lead to incorrect assignment, the analysis of the interface has been repeated by excluding Mg 2+ ions.

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