Finally, even though we could not find an optimal attribute for H3K27me3, the z -score distributions for the 1st exon results into a clear trend that agrees with the anticorrelation of H3K27me3 and expression ( Figure 4 ), despite the low IG (0.03): Up genes show almost no change, whereas Dw genes show the greatest enrichment, possibly indicating that there is an asymmetry in the pattern of this histone mark for silencing. 3.4.
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Predictive models of gene regulation from high-throughput epigenomics data.
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