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State of progress in treating cystic fibrosis respiratory disease.

BMC Med · 2012 · PMC3425089 · PMID 22883684

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showed a trendno p-value reported
Aerosolized amiloride (an epithelial sodium channel blocker with a short half-life) not only had no clinical benefit, it showed a trend toward poorer lung function in the treated patients [ 77 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.