EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells.

Cell Commun Signal · 2012 · PMC3425323 · PMID 22873932

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did not reach statistical significanceno p-value reported

With respect to Ki67 staining the HB-EGF effect did not reach statistical significance, which may be explained by donor-specific variations in the monocyte’s ability to respond to various treatments in culture (H.U., unpublished observation).

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