Alcohol drinking, tobacco smoking and subtypes of haematological malignancy in the UK Million Women Study.

Previous cohort studies have reported a statistically significant decreasing trend with greater alcohol intake among drinkers for diffuse large B-cell lymphoma ( Lim et al , 2007 ; Troy et al , 2010 ), and no significant trend for Hodgkin lymphoma, follicular lymphoma, plasma cell neoplasms or any other non-Hodgkin subtype examined ( Lim et al , 2007 ; Kanda et al , 2010 ; Troy et al , 2010 ), although one study found a near-significant decreasing trend for plasma cell neoplasms ( Troy et al , 2010 ); comparable results from case–control studies were generally consistent with these findings ( Morton et al , 2005b ; Besson et al , 2006a , 2006b ).

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Tests for heterogeneity between diagnostic subgroups were highly significant.

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