AM from FP-treated mice showed impaired expression of infection induced TNF-alpha, IP-10 (CXCL-10), and interleukin 6 (IL-6), and AM also showed a trend towards impaired intracellular pathogen control following in vivo infection.
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Inhaled fluticasone propionate impairs pulmonary clearance of Klebsiella pneumoniae in mice.
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