Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients.

There was a significant trend toward more frequent history of prior second-line drug treatment, but lower HIV prevalence with longer duration of initial intensive phase ( Table S8a ) and total duration ( Table S8b ) and somewhat greater prevalence of resistance to pyrazinamide, ethambutol, fluoroquinolones, or second-line injectables with longer initial intensive or total duration.

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