showed a trendp =0.06
3 compared mono- to dual therapy and found that dual endoscopic therapy reduced the risk of recurrent bleeding (OR, 0.59; 95% CI, 0.44 to 0.88; p <0.001), risk of emergency surgery (OR, 0.66; 95% CI, 0.49 to 0.89; p =0.03), and showed a trend toward a reduction in the risk of death (OR, 0.68; 95% CI, 0.46 to 1.02; p =0.06) ( Fig. 1 ). 3 In subgroup analysis, dual therapy was significantly superior to injection therapy alone for all the outcomes considered, but failed to demonstrate that any combination of treatments is better than either mechanical therapy alone or thermal therapy alone.