A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design.

BMC Endocr Disord · 2012 · PMC3433358 · PMID 22727048

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did not reach statistical significanceno p-value reported

Although the risk of severe hypoglycaemia in women treated with insulin aspart was 28% lower, the difference did not reach statistical significance [ 24 ].

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