BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 sub-genotypes: explanation for the "BRCA paradox"?

PLoS One · 2012 · PMC3440327 · PMID 22984553

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failed to reach statistical significanceno p-value reported

The higher count CGG n allele, mostly representing high FMR1 genotypes/sub-genotypes, varied amongst the two groups as well (Mann-Whitney U = Mean Rank 231.18 low , 260.75 high ; Z = −0.069; P = 0.07) but failed to reach statistical significance ( Figure 2a ).

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