When compared to control littermates, responses to hypercapnic challenge in Htr1a RO mice were significantly decreased ( p = 0.0097), but responses to 3% CO 2 did not reach statistical significance ( p = 0.24), likely due to small response in controls in this set of experiments.
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Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors.
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