Mice treated with raclopride+quinpirole showed a trend to a reduction in the number of TH + neurons as compared to mice treated with raclopride alone, although the difference was not statistically significant.
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Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons.
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The sentences
We found a strong effect of DA depletion on the number of striatal TH + neurons with a highly significant correlation between the extent of DA loss and the increase in TH + neurons.