Barely Significant
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Biochemical characterization and cellular effects of CADASIL mutants of NOTCH3.

PLoS One · 2012 · PMC3445613 · PMID 23028706

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There was a trend towards stronger suppression of Notch responses with expression of mutant NOTCH3 (compared to WT), but this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.