PFS data was reported in 15 studies (Table 3 ), of which 13 showed a trend of longer PFS in GCN + patients than in GCN- patients, although the difference was tested for significance in only ten studies and was statistically significant only in six of them.
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EGFR gene copy number as a predictive biomarker for the treatment of metastatic colorectal cancer with anti-EGFR monoclonal antibodies: a meta-analysis.
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