Results showed that wild-type mice exhibited a moderate elevation in IL-17 and IL-22 following inoculation although this did not reach statistical significance (p>0.05 for both cytokines) ( Figure 5E ), whereas IL-23p19 −/− mice failed to produce IL-17 and IL-22 in response to Candida ( Figure 5F ).
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The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathway.
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