Barely Significant
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A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.

PLoS One · 2012 · PMC3458035 · PMID 23049789

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showed a trendp = 0.1so close (0.05 < p ≤ 0.1)
Patients with MMR-deficient tumors showed a trend towards a better 3-year overall survival (96.3% vs . 83.5%; p = 0.1, log rank).

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