Very early posttraumatic serum alterations are significantly associated to initial massive RBC substitution, injury severity, multiple organ failure and adverse clinical outcome in multiple injured patients.

Clinical outcome Patients who decease within 90 days after the traumatic event have higher Il-6 levels at 0 h and 6 h (p < 0.005, Mann Whitney Rank Sum Test), the later observation time points show a clear trend but no significances due to large variability of the data.

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