The 53 kD precursor of PS-1 was significantly increased later, at 48 h, following IL-18 addition (26%, P 0.068 (M-W), P 0.050 ( t -Test)) (Table 1 ) with the increase at 24 h approaching significance (67%, P 0.058 ( t -Test)) (Table 1 ).
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Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells.
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