Prolonged survival after sequential multimodal treatment in metastatic renal cell carcinoma: two case reports and a review of the literature.

Patients with a metachronous appearance of brain metastases more than 1 year after nephrectomy, good performance status, age of less than 50 years, minimal or no neurological deficit, and minimal extracranial metastases showed a trend toward improved survival with metastasectomy.

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