Cells isolated from CR ascites had a more epithelial phenotype and showed a trend towards enhanced expression of genes associated with CSC when compared to cells isolated from the ascites of CN patients.
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Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors.
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The sentences
Our observations in ovarian cancer that the more epithelial (EpCAM-rich) NAD spheroids exhibit the enhanced malignant potential in mice and demonstrate an increasing trend of mRNA expression of selective CSC-like markers, are not entirely consistent with the relationship that has been developed between EMT and CSC in mammary cancer [8] – [9] .