Along the same line, phosphorylation of Akt showed an increasing trend in MMP19KO livers during the recovery period, suggesting higher anti-apoptotic signaling either via IGF-1 or another pathway.
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Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis.
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The sentences
Analysis of collagen IV mRNA showed a trend towards slightly higher expression in MMP19KO than in WT livers ( Figure 4D ).