By 6 weeks post transplantation, animals receiving pieces of VM tissue showed a trend for further improvement, while those receiving dissociated cells remained at their 4 week scores.
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Transplanting intact donor tissue enhances dopamine cell survival and the predictability of motor improvements in a rat model of Parkinson's disease.
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Rotations and Dopamine Neuron Numbers Further analysis, looking at the relationship between the number of dopamine neurons in grafts and the improvement in rotation scores by animals, revealed an interesting trend ( Figure 4 ).