Influence of FCGR3A genotype on the therapeutic response to rituximab in rheumatoid arthritis: an observational cohort study.

BMJ Open · 2012 · PMC3467642 · PMID 23002160

Europe PMC DOI

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0.0560

closest p · 1.1× alpha

0.0560

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The sentences

did not reach statistical significancep=0.056so close (0.05 < p ≤ 0.1)

Experiencing a therapeutic response was more common among rheumatoid factor (RF)-positive cases as compared with RF-negative cases (OR 2.38, 1.05 to 5.39, p=0.038), and in the RF-positive group, response rates remained significantly different across FCGR3A genotype (p=0.004), but did not reach statistical significance among RF-negative cases (p=0.056).

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