Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene.

J Transl Med · 2012 · PMC3476964 · PMID 22533838

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did not reach statistical significanceno p-value reported

However, a trend towards lower concentrations of raloxifene and its metabolites in wild type individuals compared to TC group ( SLCO1B1 c.521T > C) and to non-CC group ( SLCO1B3 int7C > G) was observed, but did not reach statistical significance (Table 3 ).

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