Effectiveness of HBV vaccination in infants and prediction of HBV prevalence trend under new vaccination plan: findings of a large-scale investigation.

The prevalence of suspected hepatitis B was highest among participants aged 20–49 years and showed a trend to a sharp decrease from 20 years to zero years old.

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This is a highly significant reduction, as the rate was approximately 9%–12% for a similar age group prior to 1992 [8] and equals a reduction of an estimated 1,577,391 HBsAg carriers and a savings of US$17.8 billion for treatment of HBV infections in Zhejiang Province.

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