Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.

Regulator of G-protein signaling 1 ( RGS1 )/1q31.2, GLIS family zinc finger 3 ( GLIS3 )/9p24.2, approached significance in our study, and a further seven SNPs had P < 0.05 ( Supplementary Table 2 ), but no support for RGS1 or GLIS3 was obtained previously ( 10 ).

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