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Tryptophan hydroxylase-1 regulates immune tolerance and inflammation.

J Exp Med · 2012 · PMC3478935 · PMID 23008335

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Female Tph-1 −/− mice had significantly higher numbers of IL-17A–specific spots (P < 0.01) in comparison with all other groups, and IFN-γ–specific spots were elevated in female Tph-1 −/− mice although it did not reach statistical significance.

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