Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection.

PLoS One · 2012 · PMC3480425 · PMID 23112829

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CMV-specific CD8 T cells in HBV-infected subjects showed a trend towards higher Tim-3 expression than CMV-specific CD8 T cells in resolved or healthy controls, ( Figure 2d ), in line with the global upregulation of Tim-3 on global T cells in CHB.

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