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Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.

Skelet Muscle · 2012 · PMC3482394 · PMID 22908954

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Gastrocnemius muscle from treated mdx mice expressed significantly more PGC-1 α , cyt c mRNAs (Figure 3 E,F) in comparison to vehicle treated group but increase in PDK4 mRNA did not reach statistical significance (Figure 3 G).

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