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Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.

PLoS One · 2012 · PMC3485290 · PMID 23118926

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However, at the highest CsA dose (10 mg/kg/day) the addition of SRL or EVL showed the tendency to enhance the effect of CsA although this effect did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.