The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate.

Br J Pharmacol · 2012 · PMC3485666 · PMID 22646698

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an overall trendno p-value reported

Laboratory variables had sporadic out-of-range values but did not show an overall trend.

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a clear trendno p-value reported

Recovery to baseline (day −1) levels of ALC was observed at the end of the study (day 49) for all except the 20 mg cohort, which showed a clear trend towards returning to baseline.

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