Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN.

BMC Cancer · 2012 · PMC3492171 · PMID 22759359

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difference was apparentno p-value reported

However, a difference was apparent in Akt phosphorylation between cells overexpressing TG2 and m-TG2 which was significantly higher in TG2 overexpressing MEF tg2-/- and MCF-7 cells with db-cAMP treatment (Figure 4 ).

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