Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer.

Although this did not reach statistical significance, most likely due to the smaller subgroup available for analysis, these findings further indicate that patients with high PODXL-expressing tumours might benefit from adjuvant treatment.

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In some cases, such as HER2/neu, expression levels show highly significant correlation [ 28 ], but in other studies regarding molecular markers in adenocarcinoma of the lung [ 29 ] and in prostate cancer [ 30 ], a relationship between mRNA and protein was not observed.

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