We observed a median antigen-specific antibody EC 50 of 64 μg/mL for PfRH5 (range 55–114 μg/mL, 95% CI for mean 46–101 μg/mL), around 40% lower than that observed for PfAMA1, although this did not reach statistical significance ( Figure 1D, P = 0.055, Mann-Whitney U test).
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Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens.
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