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Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis.

Arthritis Rheum · 2011 · PMC3494292 · PMID 21739425

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Only 2 mAb, one of which had strong antithrombin binding (IS4VHi&ii/B3VL) and the other of which had no antithrombin binding (IS4VH/B3VL), displayed weak binding to FVIIa, which failed to reach statistical significance compared with control IgG ( Table 2 and Figure 1A ).

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