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SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity.

BMC Mol Biol · 2012 · PMC3495018 · PMID 22731250

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In addition, this effect was increased by co-transfection with a wild type p300 vector, but in this reporter system it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.