Systematic review of parameters of stimulation, clinical trial design characteristics, and motor outcomes in non-invasive brain stimulation in stroke.

The analysis demonstrated a highly significant increased effect size when stimulation was applied to subcortical strokes versus the mixed strokes ( p = 2.45598e−05, two-tailed Mann–Whitney U -test.) When sub-analyzed within the context of type of stimulation technique, this significant finding was reproducible for both rTMS and tDCS articles (rTMS p = 0.01115294 and tDCS p = 0.01428572, Mann–Whitney two-tailed U -test).

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Of note, the comparison trend used data searched until the end of December of 2011 in order to provide a clear trend for the whole year of 2011.

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