Barely Significant
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Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials.

BMJ · 2012 · PMC3496553 · PMID 23150473

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showed a trendno p-value reported
All of the novel oral anticoagulants (except in the small apixaban study) showed a trend towards lower rates of major bleeding compared with vitamin K antagonists, but this was significant only for rivaroxaban.

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